University of California, San Francisco
Year: 2020
Amount: $1,384,466
Status: Completed
Primary Investigator: Springer
Summary
This project focuses on assessing the impact of chronic cannabis use on cardiovascular health, specifically endothelial function. The study investigates three key aspects: (1) the impairment of vascular function by different methods of cannabis consumption (smoking, secondhand smoke, vaporizing, edibles), (2) elevation of cardiovascular risk biomarkers through chronic exposure, and (3) functional changes in endothelial cells exposed to sera from cannabis users. Preliminary findings suggest that smoking cannabis significantly impairs endothelial function, similar to tobacco, with some noted effects from edible THC use as well.
Publications
Association of Endothelial Dysfunction With Chronic Marijuana Smoking and THC-Edible Use